Scientific rigor.

Our true north in nutrition.

Publications from our team

Our team has contributed to over 500 academic papers that were published in leading peer-review journals. Our vast range of contributions reaches from internal medicine, over nutrition, microbiome and genomics to personalized nutrition and medicine.

"One-year surveillance of SARS-CoV-2 transmission of the ELISA cohort: A model for population-based monitoring of infection risk "

Christine Klein, Max Borsche, Alexander Balck, Bandik Föh, Johann Rahmöller, Elke Peters, Jan Knickmann, Miranda Lane, Eva-Juliane Vollstedt, Susanne A. Elsner , Nadja Käding, Susanne Hauswaldt, Tanja Lange, Jennifer E. Hundt, Selina Lehrian, Julia Giese, Alexander Mischnik, Stefan Niemann, Florian Maurer, Susanne Homolka, Laura Paulowski, Jan Kramer, Christoph Twesten, Christian Sina, Gabriele Gillessen-Kaesbach, Hauke Busch, Marc Ehlers, Stefan Taube  Jan Rupp, Alexander Katalinic. Science Advances 2022

"Efficacy of the Digital Therapeutic sinCephalea in the prophylaxis of migraine in patients with episodic migraine: study protocol for a digital, randomized, open-label, standard treatment controlled trial."

Schröder T, Brudermann HCB, Kühn G, Sina C, Thaçi D, Nitschke M, König IR. Trials. 2022;23(1):997.

https://doi.org/10.1186/s13063-022-06933-2

"A Digital Therapeutic Allowing a Personalized Low-Glycemic Nutrition for the Prophylaxis of Migraine: Real World Data from Two Prospective Studies."

Lelleck VV, Schulz F, Witt O, Kühn G, Klein D, Gendolla A, Evers S, Gaul C, Thaçi D, Sina C, Schröder T. Nutrients. 2022;14(14):2927.

https://doi.org/10.3390/nu14142927

"A Digital Health Application Allowing a Personalized Low-Glycemic Nutrition for the Prophylaxis of Migraine: Proof-of-Concept Data from a Retrospective Cohort Study."

Schröder T, Kühn G, Kordowski A, Jahromi SR, Gendolla A, Evers S, Gaul C, Thaçi D, König IR, Sina C. JCM. 2022;11(4):1117.

https://doi.org/10.3390/jcm11041117

"A nutritional supplement based on a synbiotic combination of Bacillus subtilis DSM 32315 and L-alanyl-L-glutamine improves glucose metabolism in healthy prediabetic subjects – A real-life post-marketing study."

Kordowski A, Tetzlaff-Lelleck VV, Speckmann B, Loh G, Künstner A, Schulz F, Schröder T, Smollich M, Sina C, tom Dieck H. Front Nutr. 2022;9:1001419.

https://doi.org/10.3389/fnut.2022.1001419

"PalatinoseTM (Isomaltulose) and Prebiotic Inulin-Type Fructans Have Beneficial Effects on Glycemic Response and Gut Microbiota Composition in Healthy Volunteers—A Real-Life, Retrospective Study of a Cohort That Participated in a Digital Nutrition Program."

Kordowski A, Künstner A, Schweitzer L, Theis S, Schröder T, Busch H, Sina C, Smollich M. Front Nutr. 2022;9:829933.

https://doi.org/10.3389/fnut.2022.829933

"GC1qR Cleavage by Caspase-1 Drives Aerobic Glycolysis in Tumor Cells."

Sünderhauf A, Raschdorf A, Hicken M, Schlichting H, Fetzer F, Brethack, Perner S, Kemper C, Ghebrehiwet, Sina C, Derer S. Front Oncol. 2020;10:575854.

https://doi.org/10.3389/fonc.2020.575854

"Saccharin Supplementation Inhibits Bacterial Growth and Reduces Experimental Colitis in Mice."

Sünderhauf A, Pagel R, Künstner A, Wagner AE, Rupp J, Ibrahim SM, Derer S, Sina C. Nutrients. 2020;12(4):1122.

https://doi.org/10.3390/nu12041122

"Short‐term high‐fat diet feeding protects from the development of experimental allergic asthma in mice."

Schröder T, Wiese AV, Ender F, Quell KM, Vollbrandt T, Duhn J, Sünderhauf A, Künstner A, Moreno-Fernandez ME, Derer S, Aherrahrou Z, Lewkowich I, Divanovic S, Sina C, Köhl J, Laumonnier Y. Clin Exp Allergy. 2019;49(9):1245-1257.

https://doi.org/10.1111/cea.13454

"Personalized nutrition in prevention and treatment of obesity."

Schröder T, Sina C. Adipositas – Ursachen, Folgeerkrankungen, Therapie. 2019;13(03):145-148.

https://doi.org/10.1055/a-0962-3295

"Thermoneutral housing exacerbates nonalcoholic fatty liver disease in mice and allows for sex-independent disease modeling."

Giles DA, Moreno-Fernandez ME, Stankiewicz TE, Graspeuntner S, Cappelletti M, Wu D, Mukherjee R, Chan CC, Lawson MJ, Klarquist J, Sünderhauf A, Softic S, Kahn CR, Stemmer K, Iwakura Y, Aronow BJ, Karns R, Steinbrecher KA, Karp CL, Sheridan R, Shanmukhappa SK, Reynaud D, Haslam DB, Sina C, Rupp J, Hogan SP, Divanovic S. Nat Med. 2017;23(7):829-838.

https://doi.org/10.1038/nm.4346

"The microbiome and autoimmunity."

Schröder T, Ibrahim S. Internist. 2017;58(5):449-455.

https://doi.org/10.1007/s00108-017-0221-4

"Lifespan effects of mitochondrial mutations."

Hirose M, Schilf P, Gupta Y, Wright MN, Wright MN, Jöhren O, Wagner AE, Sina C, Ziegler A, Ristow M, Ibrahim SM. Nature. 2016;540(7633):E13-E14.

https://doi.org/10.1038/nature20778

"Mitochondrial gene polymorphisms alter hepatic cellular energy metabolism and aggravate diet-induced non-alcoholic steatohepatitis."

Schröder T, Kucharczyk D, Bär F, Pagel R, Derer S, Jendrek ST, Sünderhauf A, Brethack AK, Hirose M, Möller S, Künstner A, Bischof J, Weyers I, Heeren J, Koczan D, Schmid SM, Divanovic S, Giles DA, Adamski J, Fellermann K, Lehnert H, Köhl J, Ibrahim S, Sina C. Molecular Metabolism. 2016;5(4):283-295.

https://doi.org/10.1016/j.molmet.2016.01.010

"Liver steatosis is a risk factor for hepatotoxicity in patients with inflammatory bowel disease under immunosuppressive treatment."

Schröder T, Schmidt KJ, Olsen V, Möller S, Mackenroth T, Sina C, Lehnert H, Fellermann K, Büning. European Journal of Gastroenterology & Hepatology. 2015;27(6):698-704.

https://doi.org/10.1097/MEG.0000000000000350

"A Digital Health Application Allowing a Personalized Low-Glycemic Nutrition for the Prophylaxis of Migraine: Proof-of-Concept Data from a Retrospective Cohort Study"

Torsten Schröder, Gianna Kühn, Anna Kordowski, Soodeh Razeghi Jahromi, Astrid Gendolla, Stefan Evers, Charly Gaul, Diamant Thaçi, Inke Regina König and Christian Sina
Clin. Med. 2022, 11,1117. 
https://doi.org/10.3390/jcm11041117

"GC1qR Cleavage by Caspase-1 Drives Aerobic Glycolysis in Tumor Cells."

Sünderhauf, A., Raschdorf, A., Hicken, M., Brethack, A.-K., Perner, S., Kemper, C., Ghebrehiwet, B., Sina, C., and Derer, S. – Frontiers in Oncology epub ahead of print 2020
https://doi.org/10.3389/fonc.2020.575854

"Saccharin Supplementation Inhibits Bacterial Growth and Reduces Experimental Colitis in Mice."

Sünderhauf A, Pagel R, Künstner A, Wagner AE, Rupp J, Ibrahim SM, Derer S, Sina C.
Nutrients 2020 Apr 17;12(4):1122. 
https://doi.org/10.3390/nu12041122  PMID: 32316544 Free PMC article.

"Thermoneutral housing exacerbates nonalcoholic fatty liver disease in mice and allows for sex-independent disease modeling."

Giles DA, Moreno-Fernandez ME, Stankiewicz TE, Graspeuntner S, Cappelletti M, Wu D, Mukherjee R, Chan CC, Lawson MJ, Klarquist J, Sünderhauf A, Softic S, Kahn CR, Stemmer K, Iwakura Y, Aronow BJ, Karns R, Steinbrecher KA, Karp CL, Sheridan R, Shanmukhappa SK, Reynaud D, Haslam DB, Sina C, Rupp J, Hogan SP, Divanovic S- Nat Med. 2017 Jul ;23(7):829-838
DOI: 10.1038/nm.4346  PMID: 28604704 Free PMC article

"Lifespan effects of mitochondrial mutations"

Hirose M, Schilf P, Gupta Y, Wright MN, Wright MN, Jöhren O, Wagner AE, Sina C, Ziegler A, Ristow M, Ibrahim SM. – Nature. 2016 Dec 14;540(7633):E13-E14
DOI: 10.1038/nature20778  PMID: 27974775

"Mitochondrial gene polymorphisms alter hepatic cellular energy metabolism and aggravate diet-induced non-alcoholic steatohepatitis"

Schröder T, Kucharczyk D, Bär F, Pagel R, Derer S, Jendrek ST, Sünderhauf A, Brethack AK, Hirose M, Möller S, Künstner A, Bischof J, Weyers I, Heeren J, Koczan D, Schmid SM, Divanovic S, Giles DA, Adamski J, Fellermann K, Lehnert H, Köhl J, Ibrahim S, Sina C.Mol Metab. 2016 Feb 2;5(4):283-295. 
DOI: 10.1016/j.molmet.2016.01.010  PMID: 27069868 Free PMC article

"Short-term high fat diet feeding protects from the development of experimental allergic asthma in mice. "

Schröder T, Wiese AV, Ender F, Quell KM, Vollbrandt T, Duhn J, Sünderhauf A, Künstner A, Moreno-Fernandez ME, Derer S, Aherrahrou Z, Lewkowich I, Divanovic S, Sina C, Köhl J, Laumonnier Y – Clin Exp Allergy. 2019 Sep; 49(9):1245-1257.
DOI: 10.1111/cea.13454 PubMed PMID: 31265181.

"Liver steatosis is a risk factor for hepatotoxicity in patients with inflammatory bowel disease under immunosuppressive treatment."

Schröder T*, Schmidt KJ*, Olsen V, Möller S, Mackenroth T, Sina C, Lehnert H, Fellermann K, Büning J – Gastroenterol Hepatol. 2015 Jun;27(6):698-704.
DOI: 10.1097/MEG.0000000000000350  PubMed PMID: 25923946

"The microbiome and autoimmunity."

Schröder T, Ibrahim S – Internist (Berl). 2017 May;58(5):449-455.
DOI: 10.1007/s00108-017-0221-4  PubMed PMID: 28321459

"Personalized nutrition in prevention and treatment of obesity."

Schröder T, Sina C Adipositas – Ursachen, Folgeerkrankungen, Therapie. 2019; 13(03): 145-148
DOI: 10.1055/a-0962-3295

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